Ginger has long been used as a traditional medicine to treat various conditions and symptoms, including vomiting, arthritis pain, and common cold, and a recent study suggests that ginger extract (GE) may slow the growth of prostate cancer.
According to an online article published in the British Journal of Nutrition, Ritu Aneja, associate professor of Biology, discovered that ginger extract had significant effects in inhibiting the growth of cancer cells and inducing cell death in a spectrum of prostate cancer cells.
Despite a few studies have been done on the anti-cancer effects of ginger, Aneja’s lab prefers to take a more holistic approach to investigate the types of molecules involved.
“The present study is the first report to describe identification and detailed evaluation of in vitro and in vivo anticancer activity of whole ginger extract in the therapeutic management of human prostate cancer,” the researcher said.
Data evaluation shows that humans would have to consume only about 3½ ounces of whole ginger extract in their daily diet to achieve the beneficial effects.
In addition, animal studies revealed that the extract did not show significant toxicity to normal tissues, such as bone marrow and gut. Research revealed very good tumor regression by 56 percent after 8 weeks of 100 mg/kg GE treatment, compared with control experiments.
The ginger was obtained from the local farmer’s market and extracts were prepared by soaking grated ginger in methanol overnight for four consecutive days.
Although further research is needed, this study suggests that ginger extract has anticancer effects against prostate cancer cells.
The researchers performed allometric scaling calculations to extrapolate the mice dosage to humans, and the human equivalent dose of the ginger extract was found to be approximately 567 mg for a 70 kg adult, which perhaps can be obtained from about 100 g of fresh ginger.